Article
Common variation in the vitamin D receptor gene and risk of inflammatory bowel disease in an Irish case-control study.
European journal of gastroenterology & hepatology - 1 Sept 2011
Hughes David J, McManus Ross, Neary Paul, O'morain Colm, O'sullivan Maria
Abstract excerpt
OBJECTIVE: Vitamin D may protect against the development of inflammatory bowel disease (IBD). Several preliminary studies in separate geographical locations suggest that these effects may be partly mediated by genetic variants of the vitamin D receptor (VDR). The data, however, are yet to be confirmed in large European cohorts. This study aimed to determine if common VDR polymorphisms affected IBD risk in an...
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