Vitamin D receptor gene polymorphism associated with inflammatory bowel disease in New Zealand males

Abstract excerpt

Sirs, Vitamin D has been implicated as a key regulator of innate immunity in humans1–3 and association studies have linked single nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene with autoimmune or inflammatory disorders, including inflammatory bowel disease (IBD). We read with interest a previous report,1 which described a male-specific association of a SNP (rs731236) in the VDR gene with...

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