Article
Coeliac disease and gastrointestinal symptom screening in adult first-degree relatives.
Journal of gastroenterology and hepatology - 1 Dec 2017
Vaquero Luis, Rodríguez-Martín Laura, Alvarez-Cuenllas Begoña, Hernando Mercedes, Iglesias-Blazquez Cristina, Menéndez-Arias Cristina, Vivas Santiago
Abstract excerpt
BACKGROUND AND AIM: The first-degree relatives (FDRs) of patients with coeliac disease are the main risk group for disease development. The study aims to evaluate the screening strategy in FDRs with negative coeliac serology based on human leukocyte antigen (HLA) genotyping, followed by duodenal biopsy, and to analyze the prevalence of gastrointestinal symptoms and the influence of gluten intake. METHODS: Adult...
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