Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of Mating in <i>Candida albicans</i> by Construction of <i>MTL</i> a and <i>MTL</i> α Strains

14 Jul 2000

Abstract excerpt

Although the diploid fungus Candida albicans, a human pathogen, has been thought to have no sexual cycle, it normally possesses mating-type-like orthologs (MTL) of both of the Saccharomyces cerevisiae mating-type genes (MAT) a and alpha. When strains containing only MTLa or MTLalpha were constructed by the loss of one homolog of chromosome 5, the site of the MTL loci, MTLa and MTLalpha strains mated, but like...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal and yeast genetics research
Share to Fungal Infections and Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10894781
DOI: 10.1126/science.289.5477.310

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of Mating in <i>Candida albicans</i> by Construction of <i>MTL</i> a and <i>MTL</i> α StrainsPMID 10894781Read ↗

Evidence for Mating of the "Asexual" Yeast <i>Candida albicans</i> in a Mammalian HostSemantic proximity Read ↗

Identification of a Mating Type-Like Locus in the Asexual Pathogenic Yeast <i>Candida albicans</i>Semantic proximity Read ↗

Many of the genes required for mating in <i>Saccharomyces cerevisiae</i> are also required for mating in <i>Candida albicans</i>Semantic proximity Read ↗

Selective Advantages of a Parasexual Cycle for the Yeast Candida albicans.Semantic proximity Read ↗

Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains.Semantic proximity Read ↗

A single Ho-induced double-strand break at the <i>MAT</i> locus is lethal in <i>Candida glabrata</i>Semantic proximity Read ↗

Heterozygosity of genes on the sex chromosome regulates <i>Candida albicans</i> virulenceSemantic proximity Read ↗

Three mating type-like loci in Candida glabrata.Semantic proximity Read ↗

Mating-type locus homozygosis, phenotypic switching and mating: a unique sequence of dependencies in Candida albicans.Semantic proximity Read ↗

Increased virulence and competitive advantage of a/alpha over a/a or alpha/alpha offspring conserves the mating system of Candida albicans.Semantic proximity Read ↗

Cell biology of mating in Candida albicans.Semantic proximity Read ↗

Homozygosity at the MTL locus in clinical strains of Candida albicans: karyotypic rearrangements and tetraploid formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.