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Article

Evidence for Mating of the "Asexual" Yeast <i>Candida albicans</i> in a Mammalian Host

14 Jul 2000

Abstract excerpt

Since its classification nearly 80 years ago, the human pathogen Candida albicans has been designated as an asexual yeast. In this report, we describe the construction of C. albicans strains that were subtly altered at the mating-type-like (MTL) locus, a cluster of genes that resembles the mating-type loci of other fungi. These derivatives were capable of mating after inoculation into a mammalian host. C....

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Identifiers

PMID: 10894780
DOI: 10.1126/science.289.5477.307

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Related research

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Research trail→

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Evidence for Mating of the "Asexual" Yeast <i>Candida albicans</i> in a Mammalian HostPMID 10894780Read ↗

Induction of Mating in <i>Candida albicans</i> by Construction of <i>MTL</i> a and <i>MTL</i> α StrainsSemantic proximity Read ↗

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Many of the genes required for mating in <i>Saccharomyces cerevisiae</i> are also required for mating in <i>Candida albicans</i>Semantic proximity Read ↗

Genetics of Candida albicans, a Diploid Human Fungal PathogenSemantic proximity Read ↗

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Increased virulence and competitive advantage of a/alpha over a/a or alpha/alpha offspring conserves the mating system of Candida albicans.Semantic proximity Read ↗

Selective Advantages of a Parasexual Cycle for the Yeast Candida albicans.Semantic proximity Read ↗

Mating is rare within as well as between clades of the human pathogen Candida albicansSemantic proximity Read ↗

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