Article
Molecular and biological analysis of carcinoma of the small intestine: beta-catenin gene mutation by interstitial deletion involving exon 3 and replication error phenotype.
The American journal of gastroenterology - 1 Jun 2000
Murata M, Iwao K, Miyoshi Y, Nagasawa Y, Ohta T, Shibata K, Oda K, Wada H, Tominaga S, Matsuda Y, Ohsawa M, Nakamura Y, Shimano T
Abstract excerpt
The genetic mechanisms of carcinomas of the small intestine are not well understood. We report the results of analysis of genetic alterations in a case of small intestinal carcinoma. A tumor in the terminal ileum was resected in a 59-yr-old woman. Histologically, the tumor was classified as well-differentiated adenocarcinoma. We screened for genetic alterations in adenomatous polyposis coli (APC), beta-catenin,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.