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Article

A Caenorhabditis elegans type I TGF beta receptor can function in the absence of type II kinase to promote larval development.

Development (Cambridge, England) - 1 Aug 2000

Gunther C V, Georgi L L, Riddle D L

Abstract excerpt

The daf-4 gene encodes a type II bone morphogenetic protein receptor in Caenorhabditis elegans that regulates dauer larva formation, body size and male tail patterning. The putative type I receptor partner for DAF-4 in regulating dauer larva formation is DAF-1. Genetic tests of the mechanism of activation of these receptors show that DAF-1 can signal in the absence of DAF-4 kinase activity. A daf-1 mutation...

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Identifiers

PMID: 10887089
DOI: 10.1242/dev.127.15.3337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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