Article
Overlapping but distinct RNA elements control repression and activation of nanos translation.
Molecular cell - 1 Mar 2000
Crucs S, Chatterjee S, Gavis E R
Abstract excerpt
Spatially restricted synthesis of Nanos protein in the Drosophila embryo is essential for anterior-posterior patterning. Nanos translation is restricted to the posterior of the embryo by translational repression of nanos mRNA throughout the bulk cytoplasm and selective activation of posteriorly localized nanos mRNA. A 90-nucleotide translational control element (TCE) mediates translational repression. We show...
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