Article
Alternative splicing generates a family of putative secreted and membrane-associated MUC4 mucins.
European journal of biochemistry - 1 Jul 2000
Moniaux N, Escande F, Batra S K, Porchet N, Laine A, Aubert J P
Abstract excerpt
The MUC4 mucin gene encodes a putative membrane-anchored mucin with predicted size of 930 kDa, for its 26.5-kb allele. It is composed of two regions, the 850-kDa mucin-type subunit MUC4alpha and the 80-kDa membrane-associated subunit MUC4beta. In this study, we cloned and characterized unique MUC4 cDNA sequences that differ from the originally published sequence. Eight alternative splice events located downstream...
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