Article
Localization of a quantitative trait locus via a Bayesian approach.
Biometrics - 1 Mar 2000
George A W, Mengersen K L, Davis G P
Abstract excerpt
A Bayesian approach to the direct mapping of a quantitative trait locus (QTL), fully utilizing information from multiple linked gene markers, is presented in this paper. The joint posterior distribution (a mixture distribution modeling the linkage between a biallelic QTL and N gene markers) is computationally challenging and invites exploration via Markov chain Monte Carlo methods. The parameter's complete...
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