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Article

Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice.

Circulation - 4 Jul 2000

Shi W, Haberland M E, Jien M L, Shih D M, Lusis A J

Abstract excerpt

BACKGROUND: Oxidized LDL has been found within the subendothelial space, and it exhibits numerous atherogenic properties, including induction of inflammatory genes. We examined the possibility that variations in endothelial response to minimally modified LDL (MM-LDL) constitute one of the genetic components in atherosclerosis. METHODS AND RESULTS: By a novel explant technique, endothelial cells (ECs) were...

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Source

Identifiers

PMID: 10880418
DOI: 10.1161/01.cir.102.1.75

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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