Article
Differential response of vascular smooth muscle cells to oxidized LDL in mouse strains with different atherosclerosis susceptibility.
Atherosclerosis - 1 Nov 2006
Miyoshi Toru, Tian Jing, Matsumoto Alan H, Shi Weibin
Abstract excerpt
Oxidized low-density lipoprotein (LDL) has numerous atherogenic properties, including induction of inflammatory genes, and vascular smooth muscle cells (VSMC) are involved in the development of atherosclerosis. In this study, we examined whether variations of VSMC in the capacity to oxidize LDL or in response to minimally modified LDL (MM-LDL) constitute a genetic component in atherosclerosis. VSMC were isolated...
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