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Article

Comparison of sequencing by hybridization and cycle sequencing for genotyping of human immunodeficiency virus type 1 reverse transcriptase.

Journal of clinical microbiology - 1 Jul 2000

Hanna G J, Johnson V A, Kuritzkes D R, Richman D D, Martinez-Picado J, Sutton L, Hazelwood J D, D'Aquila R T

Abstract excerpt

The performances of two methods of nucleotide sequencing were compared for the detection of drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase (RT) in viruses isolated from highly RT inhibitor-experienced individuals. Of 11,677 amino acids deduced from population PCR products by both cycle sequencing and sequencing by hybridization to high-density arrays of oligonucleotide...

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Identifiers

PMID: 10878069
DOI: 10.1128/JCM.38.7.2715-2721.2000
PMCID: PMC87006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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