Article
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement.
Nature structural biology - 1 Jul 2000
Verdecia M A, Huang H, Dutil E, Kaiser D A, Hunter T, Noel J P
Abstract excerpt
Survivin is a 16.5 kDa protein that is expressed during the G2/M phase of the cell cycle and is hypothesized to inhibit a default apoptotic cascade initiated in mitosis. This inhibitory function is coupled to survivin's localization to the mitotic spindle. To begin to address the structural basis...
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