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Article

Mitochondrial DNA sequence diversity in bipolar affective disorder.

The American journal of psychiatry - 1 Jul 2000

McMahon F J, Chen Y S, Patel S, Kokoszka J, Brown M D, Torroni A, DePaulo J R, Wallace D C

Abstract excerpt

OBJECTIVE: Point mutations in mitochondrial DNA (mtDNA) are one mechanism that could explain the apparent excess maternal transmission of bipolar affective disorder observed in some families. The authors sequenced the mtDNA from probands with bipolar disorder and tested nucleotide variants for association with the disorder. METHOD: The entire 16.5 kilobase mitochondrial genome was sequenced in nine unrelated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10873911
DOI: 10.1176/appi.ajp.157.7.1058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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