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Article

An Exploratory Case-Control Study for Mitochondrial DNA G10398A in Bipolar I Disorder Patients with a Family History of Affective Disorders.

The Nigerian postgraduate medical journal - 1 Jul 2024

Mishra Rajan, Quraishi Rizwana, Deep Raman, Jain Raka

Abstract excerpt

BACKGROUND: The mitochondrial DNA (mtDNA) G10398A polymorphism has been associated with bipolar disorder (BD). It leads to an amino acid substitution within NADH dehydrogenase subunit, thereby altering the mitochondrial complex I function. This exploratory case-control study assesses the association of mtDNA G10398A with the risk of BD and its relationship to clinical variables in Indian patients. METHODS: Cases...

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Identifiers

PMID: 39219346
DOI: 10.4103/npmj.npmj_119_24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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