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Article

Cdc28 activates exit from mitosis in budding yeast.

The Journal of cell biology - 26 Jun 2000

Rudner A D, Hardwick K G, Murray A W

Abstract excerpt

The activity of the cyclin-dependent kinase 1 (Cdk1), Cdc28, inhibits the transition from anaphase to G1 in budding yeast. CDC28-T18V, Y19F (CDC28-VF), a mutant that lacks inhibitory phosphorylation sites, delays the exit from mitosis and is hypersensitive to perturbations that arrest cells in mitosis. Surprisingly, this behavior is not due to a lack of inhibitory phosphorylation or increased kinase activity, but...

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Identifiers

PMID: 10871278
DOI: 10.1083/jcb.149.7.1361
PMCID: PMC2175138

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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