Article
Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo.
Developmental biology - 1 Jul 2000
Tsang T E, Shawlot W, Kinder S J, Kobayashi A, Kwan K M, Schughart K, Kania A, Jessell T M, Behringer R R, Tam P P
Abstract excerpt
During gastrulation and early organogenesis, Lim1 is expressed in the visceral endoderm, the anterior mesendoderm, and the lateral mesoderm that comprises the lateral plate and intermediate mesoderm. A previous study has reported that kidneys and gonads are missing in the Lim1 null mutants (W. Shawlot and R. R. Behringer, 1995, Nature 374, 425-430). Results of the present study show that in the early...
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