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Article

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

1 Jul 2000

Abstract excerpt

Down syndrome is one of the major causes of mental retardation and congenital heart malformations. Other common clinical features of Down syndrome include gastrointestinal anomalies, immune system defects and Alzheimer's disease pathological and neurochemical changes. The most likely consequence of the presence of three copies of chromosome 21 is the overexpression of its resident genes, a fact which must...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10861295
DOI: 10.1093/hmg/9.11.1681

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DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathwaysPMID 10861295Read ↗

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