Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Detection of genotypic and phenotypic drug-resistant HIV-1 in patients receiving antiretroviral therapy].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases - 1 May 2000

Mori H, Kojima Y, Kawahata T, Otake T, Oishi I

Abstract excerpt

We have analyzed the sequences of HIV-1 reverse transcriptase and protease genes in peripheral blood mononuclear cells obtained from patients receiving antiretroviral therapy to evaluate the drug resistance-associated mutations. Of 84 HIV-1-infected individuals treated with reverse transcriptase inhibitors, 43 (51.2%) have been found to carry amino acid substitutions predicted to acquire drug-resistances. One to...

Topics

Acquired Immunodeficiency Syndrome
Drug Resistance, Microbial
Genotype
HIV-1
Humans
Phenotype
Protease Inhibitors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10860357
DOI: 10.11150/kansenshogakuzasshi1970.74.450

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10860357-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Detection of genotypic and phenotypic drug-resistant HIV-1 in patients receiving antiretroviral therapy].PMID 10860357Read ↗

[HIV-1 resistance against antiretroviral agents].Semantic proximity Read ↗

[Genotypic resistence in patients infected with HIV and its correlation with therapy].Semantic proximity Read ↗

[Evaluation of mutations that confer resistance to nucleoside analogs and protease inhibitors in HIV-1-infected patients. Study Group on Resistance to Antiretroviral Agents].Semantic proximity Read ↗

[Characterization of resistance in HIV. Comparison of geno- and phenotypic resistance to HIV-1 protease inhibitors].Semantic proximity Read ↗

Resistance of human immunodeficiency virus type 1 to reverse transcriptase and protease inhibitors: genotypic and phenotypic testing.Semantic proximity Read ↗

[Genotypic resistance of human immunodeficiency virus type 1 in patients with therapeutic failure].Semantic proximity Read ↗

[Drug resistance in antiretroviral therapy of HIV infection].Semantic proximity Read ↗

Frequency of genotypic and phenotypic drug-resistant HIV-1 among therapy-naive patients of the German Seroconverter Study.Semantic proximity Read ↗

Discordance between genotypic and phenotypic drug resistance profiles in human immunodeficiency virus type 1 strains isolated from peripheral blood mononuclear cells.Semantic proximity Read ↗

[Genotypic resistance to antiretroviral drugs in patients with therapeutic failure to highly active antiretroviral therapy].Semantic proximity Read ↗

Drug resistance testing in PBMCs of HIV infected patients.Semantic proximity Read ↗

Analysis of HIV-1 mutation patterns in patients failing antiretroviral therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.