Article
Discordance between genotypic and phenotypic drug resistance profiles in human immunodeficiency virus type 1 strains isolated from peripheral blood mononuclear cells.
Journal of clinical microbiology - 1 Feb 2002
Sarmati Loredana, Nicastri Emanuele, Parisi Saverio G, d'Ettorre Gabriella, Mancino Giorgio, Narciso Pasquale, Vullo Vincenzo, Andreoni Massimo
Abstract excerpt
The aim of the study was to analyze the relationship between genotypic and phenotypic drug resistance profiles of human immunodeficiency virus type 1 (HIV-1) strains isolated from patients during double-analogue nucleoside therapy. A drug-resistant HIV strain was isolated from 20 out of 25 patients, with 16 (64%) subjects carrying a virus with multiple drug resistance mutations. The most frequent resistance...
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