Article
[Genotypic resistance of human immunodeficiency virus type 1 in patients with therapeutic failure].
Medicina clinica - 14 Feb 2004
Rodríguez Martínez José Manuel, Palomares Folia José Carlos
Abstract excerpt
BACKGROUND AND OBJECTIVE: The aim of the present study is to analyse both the frequency of resistances to the different antiretrovirals and the implication of the mayor associated resistance mutations in a group of patients with therapeutic failure. PATIENTS AND METHOD: He sequence of protease (pr) and retrotranscriptase (rt) of HIV-1 isolated from blood were analysed in 284 patients. The viral load level was...
Topics
- Anti-Retroviral Agents
- DNA, Complementary
- Drug Resistance, Viral
- Gene Frequency
- Genotype
- HIV Infections
- HIV-1
- Humans
- Prevalence
- Retrospective Studies
- Reverse Transcriptase Polymerase Chain Reaction
