Article
Variation in the gene for human peroxisome proliferator activated receptor gamma (PPARgamma) does not play a major role in the development of morbid obesity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 May 2000
Evans D, Mann W A, de Heer J, Michel U, Wendt D, Kortner B, Wolf A, Beisiegel U
Abstract excerpt
OBJECTIVE: To determine the extent of variation in the gene for peroxisome proliferator activated receptor gamma (PPARgamma) in patients with morbid obesity. SUBJECTS: Two hundred morbidly obese patients who underwent gastric banding surgery and 192 healthy blood donors. Diabetics were excluded. EXPERIMENTAL: The frequency of the P115Q and P12A variants in the PPARgamma gene was determined. Single strand...
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