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Article

HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA.

Molecular and cellular biology - 1 Jul 2000

Park S, Myszka D G, Yu M, Littler S J, Laird-Offringa I A

Abstract excerpt

Human neuron-specific RNA-binding protein HuD belongs to the family of Hu proteins and consists of two N-terminal RNA recognition motifs (RRM1 and -2), a hinge region, and a C-terminal RRM (RRM3). Hu proteins can bind to AU-rich elements in the 3' untranslated regions of unstable mRNAs, causing the stabilization of certain transcripts. We have studied the interaction between HuD and prototype mRNA instability...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10848602
DOI: 10.1128/MCB.20.13.4765-4772.2000
PMCID: PMC85909

Genes

RRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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