Article
Liposome-encapsulated OK-432 specifically and sustainedly induces hepatic natural killer cells and intermediate T cell receptor cells.
Journal of gastroenterology and hepatology - 1 May 2000
Yamagiwa S, Ichida T, Sato K, Sugahara S, Yonekura K, Uchida M, Uehara K, Katoh M, Satoh H, Abo T, Asakura H
Abstract excerpt
BACKGROUND: OK-432 is a biological response modifier used in Japan to augment host immunity and is known to increase the host antitumour response. By using liposomes, which are vesicles made from phospholipids that have a structure resembling the cell membrane, we encapsulated OK-432. METHODS AND RESULTS: Encapsulated OK-432 was injected into the tail veins of mice, and its effect was compared with that of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.