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Viral Gene Expression Patterns in Human Herpesvirus 6B-Infected T Cells

28 Jul 2002

Abstract excerpt

Herpesvirus gene expression is divided into immediate-early (IE) or alpha genes, early (E) or beta genes, and late (L) or gamma genes on the basis of temporal expression and dependency on other gene products. By using real-time PCR, we have investigated the expression of 35 human herpesvirus 6B (HHV-6B) genes in T cells infected by strain PL-1. Kinetic analysis and dependency on de novo protein synthesis and...

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PMID: 12097571
DOI: 10.1128/jvi.76.15.7578-7586.2002

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