Article
Evidence for a major gene for bone mineral density in idiopathic osteoporotic families.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2000
Cardon L R, Garner C, Bennett S T, Mackay I J, Edwards R M, Cornish J, Hegde M, Murray M A, Reid I R, Cundy T
Abstract excerpt
Although there have been a number of studies indicating a heritable component for osteoporosis in middle to late adulthood, the etiology of osteoporosis in young people is uncertain. The present study aims to evaluate the extent to which genetic factors influence familial resemblance for bone mineral density (BMD) in families ascertained on the basis of young osteoporotic probands. The sample comprises eight...
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