Article
Viral genetic heterogeneity in HIV-1-infected individuals is associated with increasing use of HAART and higher viremia.
AIDS (London, England) - 5 May 2000
Ross L, Johnson M, DeMasi R, Liao Q, Graham N, Shaefer M, St Clair M
Abstract excerpt
OBJECTIVE: To assess the correlation between the outgrowth of mutant viruses (viral genetic heterogeneity), highly active antiretroviral therapy (HAART), and plasma HIV-1 RNA in a population-based observational cohort study. DESIGN: The study population consisted of 42 HIV-1-infected individuals receiving at least two nucleotide reverse transcriptase (RT) inhibitors and one or more protease inhibitors at study...
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