Article
Cloning human enamelin cDNA, chromosomal localization, and analysis of expression during tooth development.
Journal of dental research - 1 Apr 2000
Hu C C, Hart T C, Dupont B R, Chen J J, Sun X, Qian Q, Zhang C H, Jiang H, Mattern V L, Wright J T, Simmer J P
Abstract excerpt
Enamelin is the largest protein in the enamel matrix of developing teeth. In the pig, enamelin is secreted as 186-kDa phosphorylated glycoprotein, which is rapidly processed by enamel proteinases into smaller cleavage products. During the secretory stage of enamel formation, enamelin is found among the crystallites in the rod and interrod enamel and comprises roughly 5% of total matrix protein. Although the...
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