Article
Partners and pathwaysrepairing a double-strand break.
Trends in genetics : TIG - 1 Jun 2000
Haber J E
Abstract excerpt
Double-strand chromosome breaks can arise in a number of ways, by ionizing radiation, by spontaneous chromosome breaks during DNA replication, or by the programmed action of endonucleases, such as in meiosis. Broken chromosomes can be repaired either by one of several homologous recombination mechanisms, or by a number of nonhomologous repair processes. Many of these pathways compete actively for the repair of a...
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