Article
Novel sequence variants and a high frequency of recurrent polymorphisms in BRCA1 gene in Sri Lankan breast cancer patients and at risk individuals.
BMC cancer - 29 Jul 2008
De Silva Wasanthi, Karunanayake Eric H, Tennekoon Kamani H, Allen Marie, Amarasinghe Indrani, Angunawala Preethika, Ziard Mohamed H
Abstract excerpt
BACKGROUND: Breast Cancer is the most commonly diagnosed cancer among Sri Lankan women. Germline mutations in the susceptibility genes BRCA1 and BRCA2 in hereditary breast/ovarian cancer, though low in prevalence, are highly penetrant and show geographical variations. There have been only a few r...
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