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Germline BRCA1 mutation analysis in Indian breast/ovarian cancer families.

Cancer biology & therapy - 1 Jan 2000

Kumar B Vinod, Lakhotia Smita, Ankathil Ravindran, Madhavan Jayaprakash, Jayaprakash P G, Nair M Krishnan, Somasundaram Kumaravel

Abstract excerpt

Most of the predisposition to hereditary breast and ovarian cancer has been attributed to inherited defects in two tumor suppressor genes BRCA1 and BRCA2. To explore the contribution of BRCA1 mutations to hereditary breast cancer among Indian women, we examined the coding sequence of the BRCA1 gene in 14 breast cancer patients with a positive family history of breast and/or ovarian cancer. Mutation analysis was...

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Source

Identifiers

PMID: 12170759
DOI: 10.4161/cbt.1.1.33

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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