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Article

HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.

Oncogene - 20 Apr 2000

Nicot C, Mahieux R, Opavsky R, Cereseto A, Wolff L, Brady J N, Franchini G

Abstract excerpt

The c-Myb proto-oncogene is preferentially expressed in hematopoietic lineages, and highly expressed in several leukemia types. The Human T-cell Leukemia Virus Type I (HTLV-I) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL). A previous report suggested that Tax, the viral transactivator, is able to suppress the transactivation potential of c-Myb protein by competing for recruitment of CBP. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10815807
DOI: 10.1038/sj.onc.1203536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.PMID 10815807Read ↗

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