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Characterization of a newly established human pancreatic carcinoma cell line, UK Pan-1.

Cancer - 1 May 2000

Fralix K D, Ahmed M M, Mattingly C, Swiderski C, McGrath P C, Venkatasubbarao K, Kamada N, Mohiuddin M, Strodel W E, Freeman J W

Abstract excerpt

BACKGROUND: A highly tumorigenic cell line designated as UK Pan-1 was established in a surgically removed human pancreatic adenocarcinoma and characterized as having many of the genotypic and phenotypic alterations commonly found in pancreatic tumors. METHODS: The cell line was characterized by its morphology, growth rate in monolayer culture and soft agar, tumorigenicity in nude mice, and chromosomal analysis....

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PMID: 10813711
DOI: 10.1002/(sici)1097-0142(20000501)88:9<2010::aid-cncr5>3.0.co;2-5

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