Article
Progesterone receptor gene polymorphism is associated with decreased risk for breast cancer by age 50.
Cancer research - 1 May 2000
Wang-Gohrke S, Chang-Claude J, Becher H, Kieback D G, Runnebaum I B
Abstract excerpt
In a population-based case-control study for breast cancer before the age of 51 years, 554 cases and 559 age-matched controls were genotyped for the polymorphic progesterone receptor allele PROGINS. Breast cancer risk was decreased in women carrying the PROGINS allele. The odds ratio adjusted for age and study region was 0.76 [95% confidence interval (CI), 0.58-1.00]. Compared with wild-type A1/A1 homozygotes,...
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