Article
Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on long-term body weight change in Finnish type 2 diabetic and non-diabetic control subjects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Apr 2000
Sivenius K, Valve R, Lindi V, Niskanen L, Laakso M, Uusitupa M
Abstract excerpt
OBJECTIVE: To investigate the independent and combined effects of the Trp64Arg polymorphism of the beta3-adrenergic receptor (beta3AR) gene and the (-3826) A-->G polymorphism of the uncoupling protein 1 (UCP1) gene on body weight change in type 2 diabetic and non-diabetic control subjects during a 10y follow-up study. DESIGN: Controlled 10y follow-up study with baseline, 5 and 10y examinations. SUBJECTS: 70 newly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.