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Article

Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on basal metabolic rate in obese Finns.

Diabetologia - 1 Mar 1998

Valve R, Heikkinen S, Rissanen A, Laakso M, Uusitupa M

Abstract excerpt

The polymorphisms in the uncoupling protein 1 (UCP1, A to G) and beta3-adrenergic receptor (beta3-AR, Trp64Arg) genes have been suggested to be associated with an increased tendency to gain weight. We investigated the frequency of the A to G polymorphism of the UCP1 gene and its effect on basal metabolic rate (BMR) among obese Finns. We also examined the effects of the simultaneous occurrence of the polymorphisms...

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Source

Identifiers

PMID: 9541178
DOI: 10.1007/s001250050915

Genes

UCP1

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