Model-free analysis and permutation tests for allelic associations.

Abstract excerpt

In this short report, we address some practical problems in performing likelihood-based allelic association analysis of case-control data. Model-free statistics are proposed and their properties assessed by simulation, and procedures based on permutation tests are described for marker-marker as well as marker-disease associations. A memory-efficient algorithm is developed which enables several highly polymorphic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Alleles
• Share to Genotype