Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency.

The New England journal of medicine - 4 May 2000

Patel D D, Gooding M E, Parrott R E, Curtis K M, Haynes B F, Buckley R H

Abstract excerpt

BACKGROUND: Immune function can be restored in infants with severe combined immunodeficiency by transplantation of unfractionated bone marrow from HLA-identical donors or T-cell-depleted marrow stem cells from haploidentical donors, with whom there is a single haplotype mismatch, without the need for chemotherapy before transplantation or prophylaxis against graft-versus-host disease. The role of the thymus in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Leukocyte Common Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphocyte Count

Share to Plasmids

Share to Receptors, Antigen, T-Cell

Share to Severe Combined Immunodeficiency

Share to T-Lymphocytes

Share to Thymus Gland

Source

Identifiers

PMID: 10793165
DOI: 10.1056/NEJM200005043421804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency.PMID 10793165Read ↗

Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency.Semantic proximity Read ↗

Long-lasting production of new T and B cells and T-cell repertoire diversity in patients with primary immunodeficiency who had undergone stem cell transplantation: a single-centre experience.Semantic proximity Read ↗

Evaluating Thymic Function After Human Hematopoietic Stem Cell Transplantation in the Personalized Medicine EraSemantic proximity Read ↗

Early determinants of long-term T-cell reconstitution after hematopoietic stem cell transplantation for severe combined immunodeficiencySemantic proximity Read ↗

Identification of checkpoints in human T-cell development using severe combined immunodeficiency stem cells.Semantic proximity Read ↗

Direct evidence for thymic function in adult humans.Semantic proximity Read ↗

The Kinetics of Early T and B Cell Immune Recovery after Bone Marrow Transplantation in RAG-2-Deficient SCID PatientsSemantic proximity Read ↗

Severe combined immunodeficiency. A model disease for molecular immunology and therapySemantic proximity Read ↗

Effects of exogenous interleukin-7 on human thymus functionSemantic proximity Read ↗

Thymus and immune reconstitution after allogeneic hematopoietic stem cell transplantation in humans: never say never againSemantic proximity Read ↗

Effect of Graft-versus-Host Disease Prophylaxis Regimens on T and B Cell Reconstitution after Allogeneic Hematopoietic Stem Cell TransplantationSemantic proximity Read ↗

Causes of low neonatal T-cell receptor excision circles: A systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.