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Article

A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer.

British journal of clinical pharmacology - 1 May 2000

Williams M L, Bhargava P, Cherrouk I, Marshall J L, Flockhart D A, Wainer I W

Abstract excerpt

AIMS: To examine the relationship between cytochrome P450 2C19 (CYP2C19) genotype and expressed metabolic activity in 16 patients with advanced metastatic cancer. METHODS: Individual CYP2C19 genotypes were determined by PCR-based amplification, followed by restriction fragment length analysis, and compared with observed CYP2C19 metabolic activity, as determined using the log hydroxylation index of omeprazole....

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Share to Aryl Hydrocarbon Hydroxylases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10792207
DOI: 10.1046/j.1365-2125.2000.00189.x
PMCID: PMC2014949

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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