Article
Bayesian mapping of QTL in outbred F2 families allowing inference about whether F0 grandparents are homozygous or heterozygous at QTL.
Heredity - 1 Mar 2005
Hayashi T, Awata T
Abstract excerpt
In this paper, we propose a new Bayesian method for QTL analysis in outbred F2 families based on Markov chain Monte Carlo (MCMC) estimation allowing inference about whether each of F0 founders (grandparents) is homozygous or heterozygous at QTL. This, in turn, allows us to select a model accurately explaining observations of phenotypes for F2 individuals. The proposed method performs the fitting a statistical...
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