Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protective roles for ATM in cellular response to oxidative stress.

FEBS letters - 21 Apr 2000

Takao N, Li Y, Yamamoto K

Abstract excerpt

ATM (ataxia telangiectasia mutated), the gene mutated in ataxia telangiectasia, is related to a family of large phosphatidylinositol 3-kinase domain-containing proteins involved in cell cycle control and DNA repair. We found that ATM(-/-) DT40 cells were more susceptible than wild-type cells to apoptosis induced not only by ionizing radiation and bleomycin but also by non-DNA-damaging apoptotic stimuli such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia
Share to Bleomycin
Share to Catalase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dexamethasone

Share to Glutathione Peroxidase

Share to Oxidants

Share to Sphingosine

Share to X-Rays

Source

Identifiers

PMID: 10781820
DOI: 10.1016/s0014-5793(00)01422-8

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protective roles for ATM in cellular response to oxidative stress.PMID 10781820Read ↗

Cell Death and Survival Pathways Involving ATM Protein KinaseSemantic proximity Read ↗

A new role for ATMSemantic proximity Read ↗

Multiple roles of ATM in monitoring and maintaining DNA integritySemantic proximity Read ↗

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functionsSemantic proximity Read ↗

Ataxia-Telangiectasia Mutated Kinase in the Control of Oxidative Stress, Mitochondria, and Autophagy in Cancer: A Maestro With a Large OrchestraSemantic proximity Read ↗

Mitochondrial dysfunction in ataxia-telangiectasiaSemantic proximity Read ↗

ATM kinase: Much more than a DNA damage responsive protein.Semantic proximity Read ↗

ATM: from gene to function.Semantic proximity Read ↗

ATM Kinase-Dependent Regulation of Autophagy: A Key Player in Senescence?Semantic proximity Read ↗

ATM function and telomere stability.Semantic proximity Read ↗

The role of ATM in DNA damage responses and cancer.Semantic proximity Read ↗

ATM&A Key Determinant of Multiple Cellular Responses to IrradiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.