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Cell Death and Survival Pathways Involving ATM Protein Kinase

7 Oct 2021

Abstract excerpt

Cell death is the ultimate form of cellular dysfunction, and is induced by a wide range of stresses including genotoxic stresses. During genotoxic stress, two opposite cellular reactions, cellular protection through DNA repair and elimination of damaged cells by the induction of cell death, can occur in both separate and simultaneous manners. ATM (ataxia telangiectasia mutated) kinase (hereafter referred to as...

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PMID: 34680975
DOI: 10.3390/genes12101581

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