Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATM Kinase-Dependent Regulation of Autophagy: A Key Player in Senescence?

7 Jan 2021

Abstract excerpt

Increasing evidence suggests a strong interplay between autophagy and genomic stability. Recently, several papers have demonstrated a molecular connection between the DNA Damage Response (DDR) and autophagy and have explored how this link influences cell fate and the choice between apoptosis and senescence in response to different stimuli. The aberrant deregulation of this interplay is linked to the development...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to DNA Repair Mechanisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33490066
DOI: 10.3389/fcell.2020.599048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATM Kinase-Dependent Regulation of Autophagy: A Key Player in Senescence?PMID 33490066Read ↗

Ataxia-Telangiectasia Mutated Kinase in the Control of Oxidative Stress, Mitochondria, and Autophagy in Cancer: A Maestro With a Large OrchestraSemantic proximity Read ↗

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functionsSemantic proximity Read ↗

The hallmarks of aging in Ataxia-TelangiectasiaSemantic proximity Read ↗

DNA Damage Response and Autophagy: A Meaningful PartnershipSemantic proximity Read ↗

ATM function and telomere stability.Semantic proximity Read ↗

Mitochondrial dysfunction in ataxia-telangiectasiaSemantic proximity Read ↗

Differential localization of ATM is correlated with activation of distinct downstream signaling pathwaysSemantic proximity Read ↗

A new role for ATMSemantic proximity Read ↗

The ATM signaling network in development and diseaseSemantic proximity Read ↗

The versatile functions of ATM kinaseSemantic proximity Read ↗

Autophagy-related Proteins in Genome Stability: Autophagy-Dependent and Independent ActionsSemantic proximity Read ↗

ATM-associated signalling triggers the unfolded protein response and cell death in response to stressSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.