Involvement of regions in domain I in the opioid receptor sensitivity of alpha1B Ca(2+) channels.

Abstract excerpt

The structural basis of Ca(2+) channel inhibition by G proteins has received considerable attention recently, and multiple regions on Ca(2+) channels that interact with G protein subunits have been identified. We have demonstrated previously that a region extending from the N terminus to the I/II loop of the Ca(2+) channel is involved in determining the differences between alpha1B and alpha1E Ca(2+) channels with...

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