Article
Beta-thalassaemia intermedia in Lebanon.
European journal of haematology - 1 Apr 2000
Qatanani M, Taher A, Koussa S, Naaman R, Fisher C, Rugless M, Old J, Zahed L
Abstract excerpt
Approximately one third of thalassaemia patients on record in Lebanon have thalassaemia intermedia. We have analysed three factors in a panel of 73 patients with this less severe form of the disease in our population: mild beta-globin gene mutations, deletions in the alpha-globin gene and the presence of a polymorphism for the enzyme Xmn I in the Ggamma-promoter region. The results show that the most important...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- Deoxyribonucleases, Type II Site-Specific
- Female
- Globins
- Humans
- Lebanon
- Male
- Mutation
- Polymorphism, Genetic