Article
The spectrum of beta-thalassaemia mutations in the Lebanon.
Human heredity - 1 Jan 2000
Zahed L, Talhouk R, Saleh M, Abou-Jaoudeh R, Fisher C, Old J
Abstract excerpt
We screened 110 DNA samples from carriers of beta-thalassaemia, using the ARMS-PCR technique with primers for common Mediterranean mutations. Unidentified samples were subjected to a heteroduplex analysis with Universal Heteroduplex Generators covering the beta-globin gene, followed by DNA sequen...
Topics
- Community Medicine
- DNA Mutational Analysis
- Female
- Gene Frequency
- Humans
- Lebanon
- Male
- Mutation
- Prevalence
- Religion
- beta-Thalassemia