Article
Molecular analysis of α-synuclein gene in Parkinson's disease in North Karnataka, India.
Neurology India - 1 Jan 2000
Kadakol G S, Kulkarni S S, Wali G M, Gai Pramod B
Abstract excerpt
BACKGROUND: Parkinson's disease (PD) is a disabling neurological disorder characterized by progressive degeneration of dopaminergic neurons. Mutations analysis within the α-synuclein gene (SNCA) on chromosome 4 has been reported in the last decade. OBJECTIVE: To elucidate the possible role of SNCA gene in the pathogenesis of PD in Indian population specifically in north Karnataka. MATERIALS AND METHODS: The study...
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