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Article

Effect of aging on cytokine production in normal and experimental systemic lupus erythematosus-afflicted mice.

Experimental gerontology - 1 Mar 2000

Dayan M, Segal R, Globerson A, Habut B, Shearer G M, Mozes E

Abstract excerpt

Aging mice of strains susceptible to the induction of experimental systemic lupus erythematosus (SLE) develop a milder disease than young animals. To find out whether the decrease in susceptibility to disease is due to age-associated changes in cytokine profile, we first examined the secretion of cytokines by healthy mice aged 2-15 months. A gradual age-related decline in the levels of interleukin (IL)-2 and...

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Source

Identifiers

PMID: 10767581
DOI: 10.1016/s0531-5565(00)00076-0

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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