Article
Salivary Gland Mucosa-Associated Lymphoid Tissue-Type Lymphoma From Sjögren's Syndrome Patients in the Majority Express Rheumatoid Factors Affinity-Selected for IgG.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Aug 2020
Bende Richard J, Janssen Jerry, Beentjes Anna, Wormhoudt Thera A M, Wagner Koen, Haacke Erlin A, Kroese Frans G M, Guikema Jeroen E J, van Noesel Carel J M
Abstract excerpt
OBJECTIVE: Patients with Sjӧgren's syndrome (SS) have an increased risk of developing malignant B cell lymphomas, particularly mucosa-associated lymphoid tissue (MALT)-type lymphomas. We have previously shown that a predominant proportion of patients with SS-associated salivary gland MALT lymphoma express somatically hypermutated IgM with strong amino acid sequence homology with stereotypic rheumatoid factors...
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